VitriClip — Faster, Safer Cryo-EM Sample Preparation
VitriClip is a cryo-EM handling tool engineered to eliminate fragile post-vitrification transfers. By allowing you to clip grids immediately after freezing, it reduces failure points, improves grid survival, and streamlines the cold-room workflow.
Developed with input from active cryo-EM labs, VitriClip is built for researchers who need reproducibility and speed without compromising ice quality.
Why Labs Choose VitriClip
Automated ethane condensing
Ensures safety and prevents ethane-related accidents through automatic condensation, eliminating the need for manual ethane filling.
Temperature-controlled ethane cup
Maintains optimal ethane temperature for consistent freezing quality across all samples.
Fewer handling steps
Clip directly after vitrification, skip the unstable transfer from plunger to clipping area.
Seamlessly fits existing instruments
Compatible with standard clipping tools and typical Vitrobot workflows.
Workflow Integration
VitriClip seamlessly integrates into your existing cryo-EM workflow. After vitrification with your Vitrobot or similar plunging device, VitriClip allows immediate grid clipping without intermediate transfers, reducing the time your sample spends in vulnerable transition states.
This streamlined approach means fewer opportunities for ice contamination, mechanical damage, or sample loss, resulting in higher-quality grids reaching your microscope.
